Myoglobin Rapid Test
Product Background
Myoglobin (MYO) is a heme-protein normally found in skeletal and cardiac muscle with a molecular weight of 17.8kDa.It constitutes about 2 percent of total muscle protein and is responsible with transporting oxygen within the muscle cells.1 When the muscle cells are damaged, Myoglobin is released to the blood rapidly due to its relatively small size. Following the death of tissue associated with MI, Myoglobin is one of the fifirst markers to rise above normal levels. The level of Myoglobin increases measurably above baseline within 2-4 hours post-infarct, peaking at 9-12 hours and returning to baseline within 24-36 hours. A number of reports suggest the measurement of Myoglobin as a diagnostic aid in confifirming the absence of myocardial infarction with negative predictive values of up to 100% reported at certain time periods after onset of symptoms.
Intended use
The Myoglobin Rapid Test is a rapid chromatographic immunoassay for the qualitative detection of human Myogobin in whole blood, serum or plasma as an aid in the diagnosis of myocardial infarction (MI).
Operation steps and result interpretation
POSITIVE:* A colored line in the control line region (C) and the presence of one lines in the test line regions indicates a positive result. This indicates that the concentration of Myoglobin is above the minimum detection
level.
*NOTE: The intensity of the color in the test line region will vary depending on the concentration of Myoglobin, present in the specimen. Therefore, any shade of color in the test line region should be considered positive.
NEGATIVE: One colored line appears in the control line region (C). No line appears in the test line region (T).This indicates that the concentration of Myoglobin are below the minimum detection levels.
INVALID: Control line fails to appear. Insuffiffifficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test with a new test. If the
problem persists, discontinue using the test kit immediately and contact your local distributor.